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umbilical cord mesenchymal stem cells (Union Hospital, Tongji Medical College)

Development stage: Unknown
Lead developer: Union Hospital of Huazhong University of Science and Technology
Modality: Stem Cell Therapies → Cell Therapies
Administration: Intraarticular

Overview

This investigational allogeneic cell therapy consists of human umbilical cord-derived mesenchymal stem cells (UC-MSCs) developed by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology. Administered via intra-articular injection, the therapy is designed to treat knee osteoarthritis by leveraging the multi-faceted biological properties of mesenchymal stem cells. These cells exert anti-inflammatory and immunomodulatory effects within the joint microenvironment and promote the regeneration of damaged articular cartilage. Clinical development is currently focused on Phase I dose-escalation studies to evaluate the safety, tolerability, and preliminary efficacy of the treatment in patients with moderate to severe knee osteoarthritis.

Other names: human umbilical cord mesenchymal stem cell injectionhUC-MSCsUC-MSC-UH

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