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Undisclosed Program 2 (Atalanta Therapeutics)
- Development stage
- Preclinical
- Lead developer
- Atalanta Therapeutics
- Modality
- Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
01
Overview
Undisclosed Program 2 is a discovery-stage therapeutic program being developed by Atalanta Therapeutics for the treatment of central nervous system (CNS) disorders. The program utilizes Atalanta's proprietary branched siRNA (di si-RNA) technology, which features a unique dicer-substrate siRNA architecture designed for enhanced stability and distribution. This platform is engineered to achieve widespread gene silencing throughout the brain and spinal cord, addressing the delivery challenges typically associated with RNA interference in the CNS. While the specific molecular targets remain undisclosed, the program aims to leverage the RNAi pathway to downregulate the expression of multiple disease-causing genes involved in CNS pathology.
- Other names
- Atalanta CNS Program 2
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