Drug intelligence / Profile preview

Uni-GLP

Development stage
Unknown
Lead developer
Uni-Bio Science
Modality
Recombinant Proteins and Enzymes, Peptides
Administration
Subcutaneous
01

Overview

Uni-GLP is a recombinant exendin-4 injection that acts as a glucagon-like peptide-1 receptor agonist (GLP-1 RA). Developed by Uni-Bio Science Group, it is primarily indicated for the treatment of Type 2 Diabetes Mellitus. Its mechanism involves stimulating insulin secretion, inhibiting glucagon release, decreasing appetite, and slowing gastric emptying, thereby regulating blood glucose levels and promoting weight loss. Uni-GLP is biologically expressed, offering a stronger affinity to the GLP-1 receptor, improved stability, enhanced bioactivity, and lower immunogenicity compared to chemically synthesized alternatives. It is also being investigated for potential applications in obesity, cardiovascular disease, nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, Alzheimer's disease, and COVID-19.

Other names
Recombinant Exendin-4 Injection
02

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