Drug intelligence / Profile preview

UNIPlax

Development stage: Preclinical
Lead developer: PLABiologics
Modality: Cell Therapies, DNA Therapeutics → Nucleic Acid Therapeutics
Administration: Topical

Overview

UNIPlax is a polydeoxyribonucleotide (PDRN) product developed by PLABiologics, derived from human placenta-derived mesenchymal stem cells (hPD-MSCs). The product consists of DNA fragments extracted from hPD-MSCs that are fragmented via sonication to a size range of less than 500 base pairs. Although derived from an MSC platform, UNIPlax is a cell-free biomaterial rather than a live cell therapy. It is designed for tissue regeneration and wound healing applications. Its therapeutic mechanism involves promoting cellular regeneration through Adenosine A2A receptor signaling, which stimulates cell migration, angiogenesis, and the expression of vascular endothelial growth factor (VEGF). Preclinical studies have demonstrated its efficacy in promoting wound closure, granulation tissue formation, and collagen deposition.

Brand names: UNIPlax
Other names: UNIPlax®

Targets

ADORA2A (Adenosine A₂A Receptor)

Beyond the preview

Go deeper on UNIPlax.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on UNIPlax.

Explore the full profile