Unitob

Unitob is a topical ophthalmic antibiotic formulation of tobramycin, developed and marketed by Jainson Biotech. As an aminoglycoside antibiotic, tobramycin exerts its bactericidal effect by passing through the bacterial cell wall and irreversibly binding to the 30S ribosomal subunit. This binding interferes with the formation of the initiation complex between mRNA and the ribosome, leading to misreading of the genetic code and the production of nonfunctional proteins, which ultimately causes bacterial cell death. Unitob is indicated for the treatment of external infections of the eye and its adnexa, such as bacterial conjunctivitis, keratitis, and blepharitis, caused by susceptible organisms including *Staphylococcus aureus*, *Streptococcus* species, and *Pseudomonas aeruginosa*.

Brand names

Unitob

Other names

tobramycin ophthalmic