Drug intelligence / Profile preview

Univ. of Alabama at Birmingham CALR compound d6

Development stage
Unknown
Lead developer
University of Alabama at Birmingham
01

Overview

Univ. of Alabama at Birmingham CALR compound d6: sourced facts only. name: "BLI against CALR identified two high affinity binders, d4 and d6, with calculated dissociation constants of 83.2 nM (kon = 512790 M-1s-1, koff = 0.04265 s-1) and 31.2 nM (kon = 551797 M-1s-1, koff = 0.01723 s-1), respectively." [DOI:10.1158/1538-7445.am2026-5818]; target: "BLI against CALR identified two high affinity binders, d4 and d6, with calculated dissociation constants of 83.2 nM (kon = 512790 M-1s-1, koff = 0.04265 s-1) and 31.2 nM (kon = 551797 M-1s-1, koff = 0.01723 s-1), respectively." [DOI:10.1158/1538-7445.am2026-5818]; developer: "University of Alabama at Birmingham, Birmingham, AL." [DOI:10.1158/1538-7445.am2026-5818]

02

Targets

CALR (Calreticulin)

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