Drug intelligence / Profile preview

Univ. of Michigan SIRT5 compound 11

Development stage
Unknown
Lead developer
University of Michigan
01

Overview

Univ. of Michigan SIRT5 compound 11: sourced facts only. name: "In this study, we report the identification of the hit compound 11 bearing a 2-hydroxybenzoic acid functional group as a novel SIRT5-selective inhibitor via our medium-throughput thermal shift screening assay." [PMID:35932566]; target: "In this study, we report the identification of the hit compound 11 bearing a 2-hydroxybenzoic acid functional group as a novel SIRT5-selective inhibitor via our medium-throughput thermal shift screening assay." [PMID:35932566]; developer: "State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, PR China; Department of Medicinal Chemistry, College of Pharmacy and Rogel Cancer Center, University of Michigan, Ann Arbor, MI, 48109, United States." [PMID:35932566]

02

Targets

SIRT5 (NAD-dependent protein deacylase sirtuin-5, mitochondrial)

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