Univ. of South China NAMPT compound Q24

Univ. of South China NAMPT compound Q24: sourced facts only. name: "Among them, Q24 exhibited the strongest activity, showing nanomolar inhibition of NAMPT and subnanomolar antiproliferative effects against HGC-27 cells." [PMID:41722430]; target: "Among them, Q24 exhibited the strongest activity, showing nanomolar inhibition of NAMPT and subnanomolar antiproliferative effects against HGC-27 cells." [PMID:41722430]; developer: "School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China." [PMID:41722430]; modality: "we designed and synthesized a series of 29 small-molecule NAMPT inhibitors derived from lead compound 9a" [PMID:41722430]; stage: "In xenograft models, Q24 significantly inhibited tumor growth, achieving a tumor growth inhibition rate of 68.9% without notable histopathological abnormalities." [PMID:41722430]