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"Universal Serum" is a non-specific name that refers to several distinct pharmaceutical and biological products. Most commonly, it refers to **Universal Serum (Bioveta)**, a veterinary heterologous hyperimmune serum derived from horses. This product contains a polyvalent mixture of immunoglobulins (antibodies) targeting common pathogens in livestock, such as *Pasteurella multocida*, *Escherichia coli*, *Arcanobacterium pyogenes*, and *Fusobacterium necrophorum*, and is used for passive immunization and the treatment of respiratory and gastrointestinal infections in cattle, horses, sheep, and pigs. In human medicine, the term is often used colloquially to describe **Universal Antivenom** (e.g., the polyvalent antivenoms produced by the Pasteur Institute), which are designed to neutralize the venoms of multiple snake species. Historically, "Universal Serum" (Sérum Universel) also referred to **Quinton Marine Serum**, an isotonic seawater solution used for rehydration and mineral therapy. In laboratory settings, **Human AB Serum** is sometimes called "universal serum" because it lacks anti-A and anti-B antibodies, making it a versatile reagent for cell culture and a neutral plasma product for recipients of any blood type.
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