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The Universal Subunit Vaccine (flu prevention) is a preclinical peptide-based subunit vaccine being developed by EnGen Bio for the prevention of Type A influenza. The vaccine is designed to target the highly conserved M1 matrix protein (specifically the M1 epitope) of the influenza A virus. Unlike traditional seasonal vaccines that target the rapidly mutating surface proteins hemagglutinin and neuraminidase, this candidate focuses on a conserved internal protein to provide broad, "universal" protection against diverse influenza A strains, including seasonal and pandemic variants. The development program encompasses both human and veterinary applications.
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