Drug intelligence / Profile preview

Universität Münster GluN2B compound 13e

Development stage
Unknown
Lead developer
Universität Münster
01

Overview

Universität Münster GluN2B compound 13e: sourced facts only. name: "However, the introduction of lipophilic substituents at the quinolone N-atom resulted in more than 10-fold increased GluN2B affinity of the benzyl and benzyloxymethyl derivatives cis-13c (Ko = 36 nM) and 13e (Ko = 27 nM)." [PMID:38889396]; target: "However, the introduction of lipophilic substituents at the quinolone N-atom resulted in more than 10-fold increased GluN2B affinity of the benzyl and benzyloxymethyl derivatives cis-13c (Ko = 36 nM) and 13e (Ko = 27 nM)." [PMID:38889396]; developer: "Institut für Pharmazeutische und Medizinische Chemie, Universität Münster, Münster, Germany." [PMID:38889396]

02

Targets

GRIN2B (N-methyl-D-aspartate Receptor Subunit Combination: NR1a/NR2B)

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