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Unnamed Molecular Glue Program (Evogene)

Development stage: Preclinical
Lead developer: Evogene
Modality: Molecular Glues → Targeted Protein Degraders (TPDs) → Small Molecules

Overview

The Unnamed Molecular Glue Program is a preclinical drug discovery initiative by Evogene, developed in collaboration with an undisclosed biotechnology partner. The program leverages Evogene's ChemPass AI™ platform to identify and optimize small molecule molecular glues. These compounds are designed to modulate protein-protein interactions (PPIs) by either stabilizing or disrupting the interface between two proteins. Molecular glues typically function by inducing proximity between a target protein and another protein, such as an E3 ubiquitin ligase, to facilitate therapeutic outcomes like targeted protein degradation or functional modulation of previously 'undruggable' targets.

Other names: Evogene Molecular Glue ProgramPPI Molecular Glue ProgramEvogene-Protein-Protein Interactions (PPIs)-small molecule-molecular glue

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