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UNSW-SC-22
- Development stage
- Unknown
- Lead developer
- Children's Cancer Institute
01
Overview
UNSW-SC-22: sourced facts only. name: "UNSW-SC-22 directly bound to c-MYC and MYCN proteins at low micromolar equilibrium dissociation constant (KD) values which was demonstrated by surface plasmon resonance assay." [DOI:10.1158/1538-7445.am2024-4599]; target: "UNSW-SC-22 directly bound to c-MYC and MYCN proteins at low micromolar equilibrium dissociation constant (KD) values which was demonstrated by surface plasmon resonance assay." [DOI:10.1158/1538-7445.am2024-4599]; target: "UNSW-SC-22 directly bound to c-MYC and MYCN proteins at low micromolar equilibrium dissociation constant (KD) values which was demonstrated by surface plasmon resonance assay." [DOI:10.1158/1538-7445.am2024-4599]; developer: "1Children's Cancer Institute Australia, Sydney, Australia." [DOI:10.1158/1538-7445.am2024-4599]; stage: "In a MYCN-driven MB mouse model, we found that UNSW-SC-22 as a single agent at 90 mg/kg decreased tumor growth and prolonged survival." [DOI:10.1158/1538-7445.am2024-4599]
02
Targets
MYC (MYC proto-oncogene protein)MYCN (N-myc proto-oncogene protein)
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