Drug intelligence / Profile preview

Uqora

Development stage
Discontinued
Lead developer
Pharmavite
Modality
Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

**Uqora** is a branded oral dietary-supplement product line developed by Uqora for proactive urinary-tract health and reduction of recurrent urinary tract infection risk. The line includes formulations such as drink mixes, capsules, and probiotic products; formulations are not uniform across the brand. D-mannose is a principal ingredient in several Uqora products and is intended to act as a soluble decoy for the *Escherichia coli* type 1 fimbrial adhesin FimH, reducing bacterial attachment to the urinary tract and facilitating urinary clearance. Other formulations may include cranberry extract, vitamin C, curcumin, and Lactobacillus probiotics. A randomized, blinded 180-day study of Uqora supplement regimens in women with recurrent urinary tract infections was registered as NCT04024046 and later terminated.

Brand names
Uqora
02

Targets

FimH (Type 1 fimbrial adhesin)

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