ursodeoxycholic acid + thiamine + riboflavin

**Ursodeoxycholic acid + thiamine + riboflavin** is an oral fixed-dose soft-capsule combination containing ursodeoxycholic acid 50 mg, thiamine nitrate or mononitrate 10 mg, and riboflavin 5 mg. It is marketed as **Ursa-S** and related Ursa products by Daewoong for improvement of liver function in chronic hepatic disease and symptoms associated with hepatic dysfunction, including fatigue, dyspepsia, and anorexia. Ursodeoxycholic acid is a hydrophilic bile acid that improves bile composition and bile flow, reduces bile-acid-mediated hepatocyte injury, and has cytoprotective and anti-apoptotic effects; thiamine and riboflavin support intermediary energy metabolism as vitamin B cofactors. The exact three-component product was studied in a completed Phase 4 fatigue trial in patients with elevated liver-function tests and or fatty liver disease. ([daewoongcorp.kr](https://daewoongcorp.kr/www_corp/english/product/prod_view.asp?idx=123&mn=5b11))

Brand names

UrsaUrsa-S

Other names

ursodeoxycholic acid + riboflavin + thiamineursodeoxycholic acid + thiamine mononitrate + riboflavinursodeoxycholic acid + vitamin B1 + vitamin B2ursodiol + thiamine + riboflavin