Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
UWD-03
- Development stage
- Preclinical
- Lead developer
- Wondercel Therapeutics
- Modality
- CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
- Administration
- Intravenous
01
Overview
UWD-03 is an allogeneic chimeric antigen receptor T-cell (CAR-T) therapy currently in preclinical development by Wondercel Therapeutics. The therapy is engineered to target Glypican-3 (GPC3), a cell-surface oncofetal antigen that is highly expressed in hepatocellular carcinoma (HCC) and lung squamous cell carcinoma (LSCC), while showing minimal expression in healthy adult tissues. Unlike traditional autologous CAR-T therapies that use a patient's own cells, UWD-03 utilizes T-cells from healthy donors, which are modified to recognize GPC3-expressing tumor cells. This allogeneic approach potentially enables a more cost-effective and readily available 'off-the-shelf' treatment option for patients with GPC3-positive solid tumors.
- Other names
- UWD-03UWD03UWD 03
02
Targets
GPC3 (Glypican-3)
Beyond the preview
Go deeper on UWD-03.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on UWD-03.