Drug intelligence / Profile preview

uzedy

Development stage
Approved
Lead developer
Teva Pharmaceutical Industries
Modality
Small Molecules, Drug Delivery Systems
Administration
Subcutaneous
01

Overview

UZEDY is a long-acting, extended-release injectable formulation of risperidone indicated for the treatment of schizophrenia in adults. It is administered subcutaneously (under the skin) and utilizes proprietary SteadyTeq (BEPO) copolymer technology to provide sustained release of risperidone over one or two months per injection. UZEDY is the first subcutaneous, long-acting formulation of risperidone available in both one- and two-month dosing intervals. The mechanism of action involves antagonism at dopamine D2 receptors and serotonin 5-HT2A receptors, which helps balance neurotransmitters implicated in psychosis and mood regulation. UZEDY was developed by MedinCell using their BEPO technology and is distributed by Teva Pharmaceuticals[1][3][4][5][7][8][10].

Brand names
Uzedy
Other names
risperidone extended-release injectable suspensionTV-46000TV46000TV 46000
02

Targets

DRD2 (Dopamine D2 Receptor)HTR2A (Serotonin receptor 5-HT2A)

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