Drug intelligence / Profile preview

V-Spot Vaginal Probiotic Pessary

Development stage
Unknown
Lead developer
Amelia Bio
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Vaginal
01

Overview

V-Spot Vaginal Probiotic Pessary is a live biotherapeutic product developed by Amelia Bio, currently in Phase 2 clinical development. It is designed as a vaginally-inserted pessary that delivers specific beneficial *Lactobacillus* strains directly to the vaginal environment. The mechanism of action focuses on restoring and maintaining a healthy vaginal microbiota by bypassing the gastrointestinal tract, which is intended to improve outcomes in women with unexplained infertility. The product is being developed in collaboration with institutions such as The University of Western Australia and UNSW Sydney.

Brand names
V-Spotamelia's V-Spot Vaginal ProbioticV-Spot Vaginal Probiotic

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