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Vaccaria seeds are the dried mature seeds of *Vaccaria segetalis* (Neck.) Garcke, a botanical product widely utilized in Traditional Chinese Medicine (TCM) for auriculotherapy (auricular acupressure). In clinical practice, these seeds are typically taped to specific acupuncture points on the ear to provide continuous mechanical pressure stimulation. This technique, known as auriculopressure, is hypothesized to modulate the autonomic nervous system, particularly the vagus nerve, and influence appetite-regulating pathways in the hypothalamus. Clinical research, including randomized controlled trials like NCT04834180, has investigated the efficacy of Vaccaria seeds as a complementary therapy for obesity and weight management, demonstrating significant reductions in body mass index (BMI), waist circumference, and abdominal adiposity when combined with hypocaloric diets.
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