vaccinated donor plasma

Vaccinated donor plasma is a blood-derived therapeutic product consisting of plasma collected from individuals who have been vaccinated against SARS-CoV-2. This plasma contains high titers of vaccine-induced neutralizing antibodies and immunoglobulin G (IgG) specifically targeting the viral spike protein. It is used as a form of passive immunotherapy to provide immediate, though temporary, protection or treatment for COVID-19, particularly in immunocompromised patients or those at high risk of severe disease. Clinical evaluation, such as the study by Jiangsu Provincial People's Hospital (ChiCTR2300078690), focuses on the safety, durability of the immune response, and cost-effectiveness of this treatment compared to standard low-titer plasma.

Other names

vaccinee plasmavaccine-induced convalescent plasmaVax-CCPhigh-titer SARS-CoV-2 neutralizing antibody plasma