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Drug intelligence / Profile preview
vaccinia virus-inflamed rabbit skin extract
- Development stage
- Phase 3
- Lead developer
- Weishi Pharmaceutical
- Administration
- Intravenous
01
Overview
Lizasai is a biological drug product composed of an extract from the skin of rabbits that have been inflamed by inoculation with the vaccinia virus. Developed by Weishi Pharmaceuticals (Rugao) Co., Ltd., it is currently being evaluated in Phase II clinical trials in China for the treatment of acute ischemic stroke. The extract is a complex mixture of non-protein bioactive substances that exhibit neuroprotective, anti-inflammatory, and analgesic properties. Its mechanism of action in stroke is thought to involve the reduction of oxidative stress, inhibition of inflammatory cytokines, and stabilization of neuronal membranes, thereby limiting the progression of ischemic damage.
- Brand names
- Lizasai
- Other names
- VVRSEvaccinia virus-inflamed rabbit skin extract injection
02
Targets
IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))
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