Drug intelligence / Profile preview

vaccinium arctostaphylos extract

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

Vaccinium arctostaphylos extract is a botanical extract derived from the fruit or leaves of the Caucasian whortleberry (*Vaccinium arctostaphylos* L.), a member of the Ericaceae family native to regions like Iran and the Caucasus. Rich in anthocyanins (such as delphinidin, cyanidin, and malvidin glycosides) and phenolic compounds like chlorogenic acid and quercetin, the extract has been investigated for its potential therapeutic effects in metabolic and cardiovascular disorders. Clinical studies suggest it may possess anti-hyperglycemic, anti-dyslipidemic, and anti-hypertensive properties, potentially through the inhibition of alpha-glucosidase and modulation of oxidative stress and inflammatory markers. Additionally, experimental models have explored its neuroprotective role in conditions like glaucoma, where it appears to enhance mitochondrial enzyme activity and reduce lipid peroxidation.

Other names
Caucasian whortleberry extractCaucasian blueberry extractVaccinium arctostaphylos L. extract
02

Targets

SDH (Mitochondrial electron transport chain complex II)Sucrase-Isomaltase

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