Drug intelligence / Profile preview

vaccinium myrtillus leaf extract

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

*Vaccinium myrtillus* leaf extract, derived from the leaves of the bilberry plant, is a botanical extract traditionally utilized in folk medicine for the management of hyperglycemia and metabolic disorders. The extract is characterized by a high concentration of polyphenolic compounds, including chlorogenic acid, quercetin derivatives, rutin, and hyperoside. Its primary therapeutic mechanism involves the inhibition of key carbohydrate-metabolizing enzymes, specifically alpha-glucosidase and alpha-amylase, which serves to delay glucose absorption and reduce postprandial blood sugar levels. Recent research has explored its potential synergistic effects when combined with prebiotic fibers like inulin. Currently, it is primarily investigated as a functional food ingredient or nutraceutical for managing type 2 diabetes and improving glycemic control.

Other names
bilberry leaf extractVaccinium myrtillus L. leaf extract
02

Targets

AMY (Pancreatic alpha-amylase)Sucrase-Isomaltase

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