Drug intelligence / Profile preview

vaginal hyal gel

Development stage
Unknown
Lead developer
Crab Sinergy
Modality
Hydrogel Systems → Drug Delivery Systems
Administration
Intravaginal
01

Overview

Vaginal Hyal gel is a **topical vaginal gel** containing **hyaluronic acid** (as sodium hyaluronate) designed for the treatment and prevention of **vaginal dryness, itching, irritation, and atrophy**, particularly in peri- and postmenopausal women. **Hyaluronic acid** is a glycosaminoglycan naturally involved in tissue hydration and repair. The gel provides mucosal hydration, supports epithelial repair, and helps restore physiological vaginal conditions. **Arginine** is included to promote local vasodilation, enhancing microcirculation and potentially improving sexual arousal. The gel is formulated for intravaginal use as a non-hormonal alternative to estrogen-based therapies, improving symptoms and quality of life without systemic hormonal effects. Clinical studies show benefit in reducing dryness and atrophic symptoms, with favorable tolerability and safety profiles[1][2][3][4][6][7].

Brand names
Vaginal Hyal gelV-HyalV-HYAL Gel
02

Targets

NOS1 (nNOS)

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