Valdone

Valdone is a bio-enhanced curcumin formulation developed by the Asian Institute of Gastroenterology in India for the treatment of mild to moderate ulcerative colitis. Curcumin, a phytochemical derived from *Curcuma longa*, typically suffers from poor oral bioavailability; Valdone is specifically engineered to improve absorption, allowing for therapeutic effects at lower doses. It functions primarily as an anti-inflammatory and antioxidant agent, with its key mechanism involving the inhibition of nuclear factor-kappa B (NF-κB) signaling pathways. In clinical evaluations, it has been studied as an adjunctive therapy to 5-aminosalicylic acid (5-ASA) to induce clinical and endoscopic remission in patients with ulcerative colitis.

Brand names

Valdone

Other names

Bio-enhanced curcuminDiferuloylmethane