Vansolin

Vansolin is a brand-name formulation of vancomycin hydrochloride, a potent glycopeptide antibiotic primarily indicated for the treatment of severe infections caused by susceptible strains of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). It exerts its bactericidal effect by inhibiting the second stage of bacterial cell wall synthesis. Specifically, it binds with high affinity to the D-alanyl-D-alanine C-terminus of peptidoglycan precursors, sterically hindering the transpeptidation and transglycosylation steps required for cell wall cross-linking. This action leads to cell wall instability and subsequent bacterial lysis. Vansolin is typically administered intravenously for systemic infections such as endocarditis, septicemia, and osteomyelitis, but it may also be administered orally for the localized treatment of Clostridioides difficile-associated diarrhea and staphylococcal enterocolitis.

Brand names

Vansolin

Other names

vancomycin hydrochloridevancomycin