vaporized placebo

Vaporized Placebo is an inhaled comparator intervention used as a negative control in clinical research, specifically in studies investigating the effects of cannabinoids like Delta-8 and Delta-9 tetrahydrocannabinol (THC). In the context of Phase 1 trials conducted by Johns Hopkins University (e.g., NCT05287256), it is administered via inhalation to distinguish the pharmacological effects of active substances from non-specific effects such as expectation or the sensory experience of vaping. It contains no active pharmaceutical ingredients or cannabinoids and is typically composed of common vaporizing vehicles such as propylene glycol and vegetable glycerin.

Other names

inhaled placebo