Drug intelligence / Profile preview

varicella vaccine + MMR + DTaP

Development stage
Unknown
Lead developer
Sinovac (Dalian) Vaccine Technology
Modality
Vaccines & Immunotherapeutics
Administration
Subcutaneous, Intramuscular
01

Overview

This drug entry refers to the co-administration of Sinovac (Dalian) Vaccine Technology Co., Ltd.'s live attenuated varicella vaccine (branded as PROVARIX) with Measles, Mumps, and Rubella (MMR) and Diphtheria, Tetanus, and acellular Pertussis (DTaP) vaccines. It is currently being evaluated in a Phase IV clinical trial to assess the immunogenicity and safety of simultaneous or sequential administration in healthy children aged 18 to 24 months. PROVARIX is a live attenuated biologic vaccine targeting the varicella-zoster virus (VZV) to prevent chickenpox; it was launched in 2020 and received WHO prequalification in 2022. The study aims to confirm that the immune response to each component remains robust when these vaccines are given concurrently, a common practice in pediatric immunization schedules to reduce the number of clinical visits.

Brand names
PROVARIX
Other names
live attenuated varicella vaccine + MMR + DTaPvaricella vaccine + MMR + DTaP-Sinovac (Dalian) Vaccine Technology Co., Ltd.-chickenpox
02

Targets

FIM2/FIM3 (Fimbriae types 2 and 3)TT (Tetanus toxoid)

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