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Varilrix + Stamaril
- Development stage
- Unknown
- Lead developer
- GSK
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Subcutaneous
01
Overview
This entry refers to the use of two distinct, licensed live-attenuated vaccines, **Varilrix** and **Stamaril**, in a clinical research context led by the **University of Surrey**. Varilrix, developed by **GSK**, is a vaccine against the **Varicella-zoster virus** (chickenpox), while Stamaril, developed by **Sanofi**, is a vaccine against the **Yellow Fever virus**. These vaccines were utilized as benchmark immunogens in the **BIOVACSAFE** project, a large-scale European initiative aimed at identifying and validating biomarkers of vaccine reactogenicity and inflammation. In the specific Surrey-led study, healthy adults were immunized with either Varilrix or Stamaril to generate a training dataset of physiological, metabolic, and immune responses to help predict vaccine safety profiles in future development programs.
- Other names
- Varicella-zoster vaccineYellow Fever vaccineBIOVACSAFE study vaccines
02
Targets
YFV E (Yellow fever virus envelope protein)
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