Drug intelligence / Profile preview

vasopressin

Development stage
Approved
Lead developer
PH Health
Modality
Peptides
Administration
Intravenous, Intramuscular, Subcutaneous, Intranasal
01

Overview

Vasopressin is a peptide hormone used to increase blood pressure in patients with vasodilatory shock who are resistant to fluid and catecholamine therapy. It is also used to manage anti-diuretic hormone deficiency, such as in diabetes insipidus, by reducing urine flow through its action on renal V2 receptors. Additionally, vasopressin causes vasoconstriction via V1 receptors, which helps in increasing systemic vascular resistance and mean arterial blood pressure.

Brand names
VasostrictPitressin
Other names
antidiuretic hormone (ADH)arginine-vasopressin (AVP)
02

Targets

AVPR1B (Vasopressin V1b Receptor)AVPR2 (Arginine vasopressin V2 receptor)AVPR1A (Arginine vasopressin receptor 1A)Oxytocin receptor

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