Drug intelligence / Profile preview

Vasostatin-Apo2L

Development stage
Preclinical
Lead developer
Shanghai Qiaer Biotechnology
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Administration
Intravenous
01

Overview

**Vasostatin-Apo2L** is an investigational recombinant fusion protein developed as a potential anticancer therapy by Aida Pharmaceuticals through its Shanghai Qiaer Biotechnology subsidiary. It combines a vasostatin fragment, intended to inhibit endothelial-cell proliferation, angiogenesis, and tumor growth, with an Apo2L component corresponding to recombinant TNF-related apoptosis-inducing ligand that is intended to induce apoptosis in susceptible tumor cells through death-receptor signaling. Public company disclosures described the program as being in preclinical research; no marketing authorization, clinical dosage form, or completed clinical development program for Vasostatin-Apo2L was identified.

Other names
Vasostatin Apo2L
02

Targets

TNFRSF10A (Tumor necrosis factor receptor superfamily member 10A)TNFRSF10B (DR5)

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