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VAXiGEN arenavirus mRNA vaccine
- Development stage
- Preclinical
- Lead developer
- VAXiGEN
- Modality
- mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Vaccines & Immunotherapeutics
- Administration
- Intramuscular
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Overview
VAXiGEN's arenavirus vaccine is an mRNA-based prophylactic candidate currently in the research and preclinical stages of development. It is designed to prevent infections caused by the *Arenaviridae* family of viruses, with a specific focus on Lassa fever. The vaccine utilizes mRNA technology to deliver genetic sequences encoding viral antigens into host cells; these cells then produce the antigens to stimulate a robust immune response, including the generation of neutralizing antibodies and cellular immunity. Developed by VAXiGEN, an India-based biotechnology firm, this candidate is part of a broader pipeline of indigenous mRNA vaccines targeting high-priority infectious diseases.
- Other names
- Arenavirus mRNA vaccine (VAXiGEN)VAXiGEN Arenavirus vaccine
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