Drug intelligence / Profile preview

VB-3222

Development stage
Preclinical
Lead developer
Vyome Therapeutics
Modality
Small Molecules
Administration
Topical
01

Overview

VB-3222 is a topical wash-off anti-dandruff shampoo developed by Vyome Therapeutics for moderate adherent dandruff and scalp seborrheic dermatitis. The formulation contains zinc pyrithione and a proprietary synthetic medium-chain fatty-acid derivative used in Vyome's Molecular Replacement Therapeutics platform to potentiate antifungal activity against *Malassezia* species. In a 21-day, single-group clinical study in 25 participants with moderate dandruff, the product was reported to reduce adherent scalp flaking and pruritus and to be well tolerated. ([dovepress.com](https://www.dovepress.com/newly-developed-anti-dandruff-regimen-vb-3222-delivers-enhanced-sensor-peer-reviewed-fulltext-article-CCID))

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