Drug intelligence / Profile preview

VDPHL01

Development stage
Phase 3
Lead developer
Veradermics
Modality
Small Molecules
Administration
Oral
01

Overview

VDPHL01 is an investigational, non-hormonal oral drug being developed for the treatment of androgenetic alopecia (AGA), also known as pattern hair loss, in both men and women. It is currently in Phase 2/3 clinical trials. Unlike existing FDA-approved oral treatments for hair loss that act via hormonal mechanisms (such as finasteride), VDPHL01 does not impact hormone levels and aims to avoid associated side effects like sexual dysfunction or cardiovascular issues. The drug is administered as a modified-release tablet—8.5 mg for males and 4.5 mg for females—with dosing once or twice daily over a 12-month period in clinical studies. The precise mechanism of action has not been disclosed, but it is described as having a unique profile compared to current therapies[1][2][4][6][7].

Other names
VDPHL

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