vehicle cream

Vehicle cream (Braintree Laboratories) is an inactive topical formulation used as a placebo control in clinical trials evaluating the safety and efficacy of drug candidates for acne vulgaris, specifically the formulation known as BLI1100. Developed by Braintree Laboratories (now a part of Sebela Pharmaceuticals), this vehicle contains the same excipients and base components as the active BLI1100 cream but lacks the active pharmaceutical ingredient. In clinical studies, such as the Phase 2 trial NCT01514201, it serves to establish a baseline for comparison, allowing researchers to distinguish the therapeutic effects of the active drug from the potential effects of the cream base itself or the act of topical application.

Other names

Vehicle topical creamBLI1100 vehicle creamBLI-1100 vehicle creamBLI 1100 vehicle cream