Drug intelligence / Profile preview

venom desensitisation + Advax

Development stage
Unknown
Lead developer
Vaxine
Modality
Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
Administration
Subcutaneous
01

Overview

Venom desensitisation + Advax is an adjuvanted allergy immunotherapy vaccine being developed by Vaxine for the treatment of insect venom allergy, specifically targeting bee and ant venom. The formulation combines venom allergens with Vaxine's proprietary Advax adjuvant, which is based on delta-inulin. The mechanism of action involves inducing immune tolerance and stimulating the production of protective IgG blocking antibodies, which compete with IgE for allergen binding, thereby reducing the allergic response upon subsequent exposure to venom. It is currently in Phase 1 clinical development.

Other names
bee/ant venom allergy immunotherapyvenom immunotherapy + Advax
02

Targets

Honey bee venom allergensMyrmecia pilosula venom allergens

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