Drug intelligence / Profile preview

Ventriol-P

Development stage
Unknown
Lead developer
Healthkind Labs
Modality
Small Molecules
Administration
Oral
01

Overview

Ventriol-P is a fixed-dose combination oral syrup developed and marketed by Healthkind Labs. It contains four active ingredients: terbutaline (a bronchodilator), guaifenesin (an expectorant), bromhexine (a mucolytic), and menthol (a soothing agent). Terbutaline acts as a selective beta-2 adrenergic receptor agonist to relax bronchial smooth muscle and widen the airways. Guaifenesin increases the volume and reduces the viscosity of respiratory tract secretions, facilitating mucociliary clearance. Bromhexine thins and loosens thick phlegm by depolymerizing mucopolysaccharide fibers. Menthol stimulates TRPM8 receptors to produce a cooling sensation and relieve minor throat irritation. Ventriol-P is approved and marketed in India for the symptomatic relief of productive cough associated with bronchospasm, bronchitis, bronchial asthma, emphysema, and other bronchopulmonary disorders.

Brand names
Ventriol-P
Other names
bromhexine + guaifenesin + menthol + terbutalinebromhexine + guaiphenesin + menthol + terbutalineterbutaline + guaifenesin + menthol + bromhexineterbutaline + guaiphenesin + menthol + bromhexine
02

Targets

ADRB2 (β2)TRPM8 (Transient receptor potential cation channel subfamily M member 8)

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