Drug intelligence / Profile preview

VeonGen novel non-VEGF gene therapy

Development stage
Preclinical
Lead developer
VeonGen Therapeutics
Modality
Gene Therapies
Administration
Ophthalmic
01

Overview

VeonGen's novel non-VEGF gene therapy is an experimental therapeutic candidate currently in preclinical development for the treatment of age-related macular degeneration (AMD). Developed by VeonGen (formerly ViGeneron), this program distinguishes itself from current standard-of-care treatments by targeting a novel, undisclosed biological pathway independent of vascular endothelial growth factor (VEGF). The therapy leverages VeonGen's proprietary viral vector technology, specifically designed for efficient retinal transduction following intravitreal administration. By addressing non-VEGF mechanisms, the therapy aims to provide a new treatment option for patients who do not respond adequately to existing anti-VEGF therapies, potentially offering improved visual outcomes and a reduced treatment burden through long-term transgene expression.

Other names
ViGeneron novel non-VEGF gene therapyVeonGen novel non-VEGF AMD gene therapyViGeneron novel non-VEGF AMD gene therapy
02

Targets

ABCA4

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