Drug intelligence / Profile preview

Vertigoheel

Development stage
Unknown
Lead developer
Heel
Modality
Small Molecules
Administration
Oral, Sublingual
01

Overview

Vertigoheel is a multi-component homeopathic medicinal product developed for the treatment of vertigo of various origins. It is a fixed-dose combination consisting of four active ingredients: *Ambra grisea* (ambergris), *Anamirta cocculus* (Indian berry), *Conium maculatum* (hemlock), and *Petroleum rectificatum* (rectified petroleum). The drug is primarily used to reduce the frequency, intensity, and duration of vertigo attacks associated with conditions such as Meniere's disease, bilateral vestibulopathy, functional dizziness, and atherosclerosis-related vertigo. Its pharmacological profile includes the stimulation of cyclic nucleotide pathways (adenylate cyclase) and the inhibition of phosphodiesterase 5 (PDE5), which collectively promote vasorelaxation and improve microcirculatory perfusion in the inner ear and vertebrobasilar system. Recent preclinical research has also explored its potential as a cognitive enhancer, showing improvements in spatial and visual recognition memory in rodent models.

Brand names
Vertigoheel
02

Targets

AC (Adenylyl cyclase family)PDE5 (Phosphodiesterase 5A)

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