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Vetevel

Development stage
Unknown
Lead developer
Vetoquinol
Modality
Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Small Molecules, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
Administration
Oral
01

Overview

Vetevel is a veterinary-specific phosphate binder containing sevelamer hydrochloride, indicated for the management of hyperphosphatemia in cats and dogs with chronic kidney disease (CKD). It is a non-absorbed, cross-linked polymeric compound that acts locally within the gastrointestinal tract. By binding to dietary phosphate through ion exchange and hydrogen bonding, Vetevel prevents the absorption of phosphorus into the systemic circulation. This reduction in phosphate load is crucial for managing secondary renal hyperparathyroidism and slowing the progression of renal disease in companion animals. Unlike calcium-based binders, Vetevel does not increase serum calcium levels, reducing the risk of metastatic calcification and other complications associated with mineral-bone disorders in pets with impaired renal function.

Brand names
Vetevel
Other names
sevelamer hydrochloride
02

Targets

Pi (Inorganic phosphate)

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