Drug intelligence / Profile preview

VF001-DP HD

Development stage
Unknown
Lead developer
Tissue Therapies
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Administration
Topical
01

Overview

VF001-DP HD is a high-dose formulation of a proprietary recombinant fusion protein designed for topical application to chronic wounds, particularly venous leg ulcers. The drug consists of an engineered vitronectin motif linked to insulin-like growth factor 1 (IGF-1), creating a multi-action biologic that provides cell attachment sites and stimulates cellular proliferation in the wound bed. This mechanism enables fibroblasts and keratinocytes to attach, migrate, and proliferate within the extracellular matrix, thereby promoting wound healing by reinstating more normal tissue repair processes. The product has been evaluated as an adjunct to standard care in randomized controlled trials for chronic venous leg ulcers[5][6].

Other names
VF001-DP HDVF-001-DP HDVF 001-DP HDVF 001 DP HDVF001 DP HDVF-001 DP HD
02

Targets

IGF-1R (Insulin-like growth factor 1 receptor)

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