Drug intelligence / Profile preview

VGO-Cs01p

Development stage
Phase 1
Lead developer
Shanghai Vitalgen BioPharma
Modality
CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies, Lymphokine-Activated Killer Cells → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intravenous
01

Overview

VGO-Cs01p is an investigational cell therapy product consisting of CD7-targeted chimeric antigen receptor (CAR) natural killer (NK) cells derived from human embryonic stem cells. It is being developed for the treatment of CD7-positive relapsed or refractory acute T-lymphoblastic leukemia (R/R T-ALL), particularly in pediatric patients. The therapy aims to harness the cytotoxic potential of engineered NK cells to selectively target and eliminate malignant T-cells expressing the CD7 antigen. The product is currently under evaluation in early phase clinical trials, with a focus on safety and preliminary efficacy[1][2][3][4][6][8].

Other names
NK cell derived from human embryonic stem cells
02

Targets

CD7 (CD7 antigen)

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