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Viamass

Development stage: Unknown
Lead developer: Hizon Laboratories
Modality: Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration: Oral

Overview

Viamass is a combination pharmaceutical product primarily utilized as an appetite stimulant and nutritional support agent. It contains cyproheptadine hydrochloride, a first-generation antihistamine with significant antiserotonergic activity, alongside a complex of B-vitamins including thiamine (B1), riboflavin (B2), pyridoxine (B6), and cyanocobalamin (B12). The mechanism of action involves cyproheptadine's antagonism of serotonin receptors (specifically 5-HT2C) in the hypothalamus, which leads to an increase in appetite and food consumption. The B-complex vitamins are included to facilitate energy metabolism and address potential deficiencies in patients with poor nutritional intake. Viamass is commonly indicated for individuals suffering from anorexia, underweight conditions, or those requiring nutritional supplementation during convalescence.

Brand names: Viamass
Other names: Cyproheptadine + Vitamin B-Complex

Targets

HTR2C (5-hydroxytryptamine 2C receptor)HRH1 (Histamine H1 Receptor)HTR2A (Serotonin receptor 5-HT2A)

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