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ViAqua RNAi feed supplement

Development stage
Preclinical
Lead developer
ViAqua Therapeutics
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Administration
Oral
01

Overview

ViAqua RNAi feed supplement is an orally administered, RNA-based treatment developed by ViAqua Therapeutics for the prevention of White Spot Syndrome Virus (WSSV) in farmed shrimp. The product utilizes RNA interference (RNAi) technology, specifically encapsulated double-stranded RNA (dsRNA) particles that are incorporated into shrimp feed. These RNA molecules are designed to silence essential viral genes of WSSV, triggering an innate anti-viral response within the shrimp's cells to suppress viral replication. As shrimp lack an adaptive immune system, traditional vaccination is ineffective; this feed-based RNAi approach provides a scalable solution to address WSSV, which causes significant global economic losses in the aquaculture industry. The product is being commercialized in partnership with Skretting, a Nutreco company.

Other names
RNA-based feed supplementin-feed RNAencapsulated dsRNA particle formulation

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