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Viaskin rPT
- Development stage
- Unknown
- Lead developer
- DBV Technologies
- Modality
- Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
- Administration
- Transdermal
01
Overview
Viaskin rPT is a novel investigational **epicutaneous vaccine patch** developed to boost immunity against *Bordetella pertussis* (whooping cough)[1][3][9]. It is designed to deliver BioNet’s **genetically detoxified recombinant pertussis toxin (rPT)** directly through intact skin via DBV’s needleless, adjuvant-free Viaskin patch technology. The mechanism utilizes the skin’s immune properties for antigen presentation, aiming to reactivate pertussis toxin immunity without injections. Viaskin rPT has been explored in Phase I clinical studies for **pertussis booster vaccination** in healthy adults. The primary indication is as a **booster for pertussis immunity**, providing a potentially **non-invasive, self-administrable alternative** to traditional injected vaccines. The epicutaneous route is hypothesized to stimulate both humoral and cellular immune responses via antigen-presenting cells in the skin[1][3].
- Brand names
- Viaskin rPT
- Other names
- Viaskin rPTViaskin-PT
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