Drug intelligence / Profile preview

Vicebio SARS-CoV-2 new strain vaccine

Development stage
Preclinical
Lead developer
Sanofi
Modality
Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
Administration
Intramuscular
01

Overview

Vicebio's SARS-CoV-2 new strain vaccine is a preclinical-stage protein subunit vaccine candidate designed to target emerging variants of the SARS-CoV-2 virus. The vaccine utilizes proprietary Molecular Clamp technology, licensed from the University of Queensland, which is a protein stabilization platform that locks viral surface proteins—specifically the SARS-CoV-2 spike protein—into their optimal prefusion conformation. By maintaining this stable shape, the vaccine is intended to present the immune system with the most relevant antigenic epitopes to elicit a potent neutralizing antibody response against updated variants. Vicebio, a UK-based biopharmaceutical company, was acquired by Sanofi in 2025, and this program is part of a broader respiratory virus pipeline that leverages the Molecular Clamp platform to improve vaccine stability and immunogenicity.

Other names
SARS-CoV-2 new strain vaccineSARS-CoV2 new strain vaccineSARS-CoV 2 new strain vaccineVicebio COVID-19 vaccineSARS-CoV-2 Spike protein (new variants) vaccine
02

Targets

SARS-CoV-2 spike

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