Vicryl Plus + Monocryl Plus + PDS Plus

Vicryl Plus + Monocryl Plus + PDS Plus is a combination of three triclosan-coated absorbable surgical sutures manufactured by Ethicon, a Johnson & Johnson company. The combination includes Coated VICRYL Plus (polyglactin 910, a multifilament), MONOCRYL Plus (poliglecaprone 25, a monofilament), and PDS Plus (polydioxanone, a monofilament). Each suture is impregnated or coated with triclosan (Irgacare MP), a medical-grade antimicrobial agent designed to inhibit bacterial colonization, particularly by Gram-positive organisms such as *Staphylococcus aureus*, for up to approximately 30 days post-implantation. This combination is classified as a medical device/drug combination and is used for general soft tissue approximation and ligation. In clinical research, such as the Phase 4 trial conducted by the University of Texas Medical Branch, this combination has been evaluated for its efficacy in reducing surgical site infections (SSI) and endometritis in patients undergoing cesarean delivery.

Brand names

Coated VICRYL Plus

Other names

triclosan-coated suturesantibacterial-coated sutures