Drug intelligence / Profile preview

vildagliptin + metformin (Genix Pharma)

Development stage
Unknown
Lead developer
Genix Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

Velon-M is a fixed-dose combination of vildagliptin and metformin hydrochloride used for the treatment of type 2 diabetes mellitus. Vildagliptin is a potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor that enhances glycemic control by increasing the levels of incretin hormones, which stimulate insulin secretion and suppress glucagon release in a glucose-dependent manner. Metformin is a biguanide antihyperglycemic agent that improves glucose tolerance by lowering both basal and postprandial plasma glucose. It works by decreasing hepatic glucose production, reducing intestinal absorption of glucose, and improving insulin sensitivity. The combination is typically indicated for patients who do not achieve adequate glycemic control with metformin alone or who are already being treated with the combination of vildagliptin and metformin as separate tablets.

Brand names
Velon-M
Other names
Velon-Mvildagliptin + metformin hydrochloride
02

Targets

ND1 (Mitochondrial electron transport chain complex I)

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