vinbarbital

Vinbarbital is a hypnotic drug and barbiturate derivative developed by Sharp and Dohme in 1939. It acts as an intermediate-acting sedative-hypnotic with a pharmacological profile similar to pentobarbital. Vinbarbital enhances the activity of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the central nervous system (CNS), by binding to GABA-A receptors and increasing chloride channel opening duration. This results in CNS depression leading to sedation and hypnosis. Vinbarbital was used for sedation, analgesia (especially in obstetrics), preoperative anxiety reduction, amnesia during procedures, treatment of insomnia and epilepsy, as well as psychiatric disorders. Its use has declined due to the availability of safer alternatives[1][4][5][6][8].

Brand names

delvinalsuppoptanox

Other names

vinbarbitonebutenemalumvinbarbitalum