Drug intelligence / Profile preview

vindesine + streptozocin + cisplatin + prednisone

Development stage
Unknown
Lead developer
Pfizer
Modality
Small Molecules
Administration
Intravenous (vindesine, Streptozocin, Cisplatin), Oral (prednisone)
01

Overview

This combination consists of four individual chemotherapeutic and supportive agents: vindesine (a semisynthetic vinca alkaloid), streptozocin (an alkylating agent), cisplatin (a platinum-based alkylating agent), and prednisone (a corticosteroid). Each drug has a distinct mechanism of action and clinical use. This combination is not a marketed fixed-dose product but can be administered together as part of multi-agent chemotherapy regimens for certain malignancies, particularly when intensive treatment or symptomatic management is required. The regimen is not universally standardized and would be based on institutional or protocol-specific guidelines.

02

Targets

GR (Glucocorticoid receptor)TUBB1 (β-tubulin 1)DNA

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